Establishment of a pancreatic cancer animal model using the pancreas-targeted hydrodynamic gene delivery method

• প্রধান লেখক: Osamu Shibata (লেখক), Kenya Kamimura (লেখক), Yuto Tanaka (লেখক), Kohei Ogawa (লেখক), Takashi Owaki (লেখক), Chiyumi Oda (লেখক), Shinichi Morita (লেখক), Atsushi Kimura (লেখক), Hiroyuki Abe (লেখক), Satoshi Ikarashi (লেখক), Kazunao Hayashi (লেখক), Takeshi Yokoo (লেখক), Shuji Terai (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2022-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

This research developed an easy-to-use, reproducible pancreatic cancer animal model utilizing pancreas-targeted hydrodynamic gene delivery to deliver human pancreatic cancer-related genes to the pancreas of wild-type rats. KRASG12D-induced pancreatic intraepithelial neoplasia lesions showed malignan...