Synergistic Effect of Clinically Available Beta-Lactamase Inhibitors Combined with Cefiderocol against Carbapenemase-Producing Gram-Negative Organisms

• Main Authors: Gabriele Bianco (Author), Paolo Gaibani (Author), Sara Comini (Author), Matteo Boattini (Author), Giuliana Banche (Author), Cristina Costa (Author), Rossana Cavallo (Author), Patrice Nordmann (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of β-lactamases in reduced susceptibility or resistance to cefiderocol has been supported by recent reports. The purpose of this study was to investigate the <i>in vitro</i> impact of clinically available β-lactamase inhibitors on cefiderocol activity against characterized carba...