In silico prediction of functional loss of cst3 gene in hereditary cerebral amyloid angiopathy

• Autores principales: Piyush Choudhary (Autor), Juhee Singh (Autor), V. Karthick (Autor), V. Shanthi (Autor), R. Rajasekaran (Autor), Karuppasamy Ramanathan (Autor)
• Formato: Libro
• Publicado: Bangladesh Pharmacological Society, 2013-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The computational identification of missense mutation in CST3 (CYSTATIN 3 or CYSTATIN C) gene has been done in the present study. The missense mutations in the CST3 gene will leads to hereditary cerebral amyloid angiopathy  The initiation of the analysis was done with SIFT followed by POLYPHEN-2 and...