BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature

• Główni autorzy: Mir Ali (Autor), Celia Dawn Delozier (Autor), Uzair Chaudhary (Autor)
• Format: Książka
• Wydane: BMC, 2019-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Hereditary colon cancer is characterized by the inheritance of an abnormal gene mutation which predisposes to malignancy. Recent advances in genomic medicine have identified mutations in "novel" genes as conferring an increased risk of colorectal cancer. Mutations in th...