Tumor necrosis factor receptor associated factor 3 regulated the signaling pathway of STING/IFN-I for improving the lupus nephritis related podocyte injury and understanding its mechanism

• Κύριοι συγγραφείς: Jin-shu Chen (Συγγραφέας), Pi-hou Chen (Συγγραφέας), Yi-jin Song (Συγγραφέας), Jia-xin Wei (Συγγραφέας), Jing Sun (Συγγραφέας), Zhi-quan Xu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Editorial Department of Journal of Clinical Nephrology, 2023-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Objective To explore the effect and mechanism of TRAF3 on IgG-induced apoptosis and inflammation of human podocyte cell (HPC). Methods HPC cells were cultured in vitro and induced with purified IgG from lupus nephritis (LN) patients to create an inflammatory environment for 24h. The cells were divid...