Degradation kinetics and characterization of degradation products of losartan potassium by LC-MS/MS method

• Những tác giả chính: Dobričić Vladimir (Tác giả), Marković Bojan (Tác giả)
• Định dạng: Sách
• Được phát hành: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2019-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

This paper presents study of losartan potassium stability evaluation by liquid chromatography with UV/VIS and MS-MS detection and its degradation profile. A solution of losartan potassium was exposed to the following stress agents: 0.1 M HCl, 0.1 M NaOH, and 3% (v/v) H2O2. The analyses of losartan p...