Polysarcosine-Functionalized mRNA Lipid Nanoparticles Tailored for Immunotherapy

• Main Authors: Christoph Wilhelmy (Author), Isabell Sofia Keil (Author), Lukas Uebbing (Author), Martin A. Schroer (Author), Daniel Franke (Author), Thomas Nawroth (Author), Matthias Barz (Author), Ugur Sahin (Author), Heinrich Haas (Author), Mustafa Diken (Author), Peter Langguth (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based therapeutics, finding applications in various indications, extending beyond their recent use in vaccines for infectious diseases. However, many aspects of LNP structure and their effects on efficacy are not well charac...