Inflammation Induced by Lipopolysaccharide and Palmitic Acid Increases Cholesterol Accumulation via Enhancing Myeloid Differentiation Factor 88 Expression in HepG2 Cells

• Main Authors: Junbin Chen (Author), Yuguo Liu (Author), Huiyu Luo (Author), Guoxun Chen (Author), Zhongdaixi Zheng (Author), Tiannan Wang (Author), Xinge Hu (Author), Yue Zhao (Author), Jiaqi Tang (Author), Chuhong Su (Author), Longying Zha (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, multiple studies have shown that chronic inflammation disturbs cholesterol homeostasis and promotes its accumulation in the liver. The underlying molecular mechanism remains to be revealed. The relationship between the toll-like receptor 4 (TLR4) inflammatory signaling pathway and choleste...