Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route

• Main Authors: Arshad Mahmood (Author), Rabbia Haneef (Author), Ahmad Z. Al Meslamani (Author), Mohammad F. Bostanudin (Author), Muhammad Sohail (Author), Muhammad Sarfraz (Author), Mosab Arafat (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of kolliphore (40%), transcutol (30%), propylene glycol (20%) and oleoyl chloride...