Ventilation‐induced epithelial injury drives biological onset of lung trauma in vitro and is mitigated with prophylactic anti‐inflammatory therapeutics

• Main Authors: Eliram Nof (Author), Arbel Artzy‐Schnirman (Author), Saurabh Bhardwaj (Author), Hadas Sabatan (Author), Dan Waisman (Author), Ori Hochwald (Author), Maayan Gruber (Author), Liron Borenstein‐Levin (Author), Josué Sznitman (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Mortality rates among patients suffering from acute respiratory failure remain perplexingly high despite the maintenance of blood oxygen homeostasis during ventilatory support. The biotrauma hypothesis advocates that mechanical forces from invasive ventilation trigger immunological mediator...