Modification of -Adenosyl--Homocysteine as Inhibitor of Nonstructural Protein 5 Methyltransferase Dengue Virus Through Molecular Docking and Molecular Dynamics Simulation

• Main Authors: Usman Sumo Friend Tambunan (Author), Mochammad Arfin Fardiansyah Nasution (Author), Fauziah Azhima (Author), Arli Aditya Parikesit (Author), Erwin Prasetya Toepak (Author), Syarifuddin Idrus (Author), Djati Kerami (Author)
• Format: Book
• Published: AboutScience Srl, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue fever is still a major threat worldwide, approximately threatening two-fifths of the world's population in tropical and subtropical countries. Nonstructural protein 5 (NS5) methyltransferase enzyme plays a vital role in the process of messenger RNA capping of dengue by transferring methy...