Effects of Serotonergic Anxiolytics on the Freezing Behavior in the Elevated Open-Platform Test in Mice

• Main Authors: Shigeo Miyata (Author), Toshiko Shimoi (Author), Shoko Hirano (Author), Naoko Yamada (Author), Yoko Hata (Author), Naoki Yoshikawa (Author), Masahiro Ohsawa (Author), Junzo Kamei (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Freezing behavior is thought to be a sign of fear in animals. We examined whether the freezing behavior during the elevated open-platform stress, which is a psychological stressor without painful stimulus, is modulated by serotonergic neurotransmission and would be a useful marker for screening anxi...