Effects of opioids on local anesthesia in the rat: a codeine and tramadol study

• Main Authors: Talita Girio Carnaval (Author), Roberta Moura Sampaio (Author), Camila Bernadeli Lanfredi (Author), Maria Aparecida Borsatti (Author), Carlos Alberto Adde (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica, 2013-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Opioids are central analgesics that act on the CNS (central nervous system) and PNS (peripheral nervous system). We investigated the effects of codeine (COD) and tramadol (TRAM) on local anesthesia of the sciatic nerve. Eighty Wistar male rats received the following SC injections in the popliteal fo...