Gallic Acid Alleviates Neuropathic Pain Behaviors in Rats by Inhibiting P2X7 Receptor-Mediated NF-κB/STAT3 Signaling Pathway

• Main Authors: Runan Yang (Author), Zijing Li (Author), Yuting Zou (Author), Jingjian Yang (Author), Lin Li (Author), Xiumei Xu (Author), Günther Schmalzing (Author), Hong Nie (Author), Guilin Li (Author), Shuangmei Liu (Author), Shangdong Liang (Author), Changshui Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuropathic pain is a complex disease with high incidence. Adenosine triphosphate (ATP) and its activated P2X7 receptor are involved in the signal transmission of neuropathic pain. Gallic acid (3,4,5-trihydroxybenzoic acid) is a traditional Chinese medicine obtained from natural plants that exhibit...