When will the immune-stimulating antibody conjugates (ISACs) be transferred from bench to bedside?

• Main Authors: Chen Fu (Author), Weiwei Tong (Author), Lifeng Yu (Author), Yuxi Miao (Author), Qian Wei (Author), Zhaojin Yu (Author), Bo Chen (Author), Minjie Wei (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunostimulatory antibody conjugates (ISACs) as a promising new generation of targeted therapeutic antibody-drug conjugates (ADCs), that not only activate innate immunity but also stimulate adaptive immunity, providing a dual therapeutic effect to eliminate tumor cells. However, several ISACs are s...