Lafutidine-Induced Increase in Intracellular Ca2+ Concentrations in PC12 and Endothelial Cells

• Main Authors: Kana Kunieda (Author), Akiyoshi Someya (Author), Syunji Horie (Author), Hirofusa Ajioka (Author), Toshihiko Murayama (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lafutidine, a histamine H2 receptor antagonist, exerts gastroprotective effects in addition to gastric antisecretory activity. The gastrointestinal protective effects of lafutidine are mediated by capsaicin-sensitive neurons, where capsaicin excites neurons by opening a member of the transient recep...