A Multifunctional Hybrid Nanocarrier for Non-Invasive siRNA Delivery to the Retina

• Main Authors: Shogo Nishida (Author), Yuuki Takashima (Author), Ryotaro Udagawa (Author), Hisako Ibaraki (Author), Yasuo Seta (Author), Hiroshi Ishihara (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug therapy for retinal diseases (e.g., age-related macular degeneration, the leading cause of blindness) is generally performed by invasive intravitreal injection because of poor drug delivery caused by the blood-retinal barrier (BRB). This study aimed to develop a nanocarrier for the non-invasive...