Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples

The success of monoclonal antibody (mAb) therapeutics have increased pharmaceutical investment in mAb production, which has led to a greater demand of technologies to efficiently characterize these biotherapeutics. The large size and heterogeneity of mAbs require the measurement of multiple critical...

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Main Authors: Zachary D. Dunn (Author), Jayesh Desai (Author), Gabriel M. Leme (Author), Dwight R. Stoll (Author), Douglas D. Richardson (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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