Virtual Clinical Trials Guided Design of an Age-Appropriate Formulation and Dosing Strategy of Nifedipine for Paediatric Use

Virtual Clinical Trials Guided Design of an Age-Appropriate Formulation and Dosing Strategy of Nifedipine for Paediatric Use

The rapid onset of action of nifedipine causes a precipitous reduction in blood pressure leading to adverse effects associated with reflex sympathetic nervous system (SNS) activation, including tachycardia and worsening myocardial and cerebrovascular ischemia. As a result, short acting nifedipine pr...

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Main Authors: Dilawar Khan (Author), Raj Badhan (Author), Daniel J. Kirby (Author), Simon Bryson (Author), Maryam Shah (Author), Afzal Rahman Mohammed (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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