Spadin Selectively Antagonizes Arachidonic Acid Activation of TREK-1 Channels

TREK-1 channel activity is a critical regulator of neuronal, cardiac, and smooth muscle physiology and pathology. The antidepressant peptide, spadin, has been proposed to be a TREK-1-specific blocker. Here we sought to examine the mechanism of action underlying spadin inhibition of TREK-1 channels....

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Bibliographic Details
Main Authors: Ruolin Ma (Author), Anthony Lewis (Author)
Format: Book
Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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