Enhanced Water Solubility and Oral Bioavailability of Paclitaxel Crystal Powders through an Innovative Antisolvent Precipitation Process: Antisolvent Crystallization Using Ionic Liquids as Solvent

Enhanced Water Solubility and Oral Bioavailability of Paclitaxel Crystal Powders through an Innovative Antisolvent Precipitation Process: Antisolvent Crystallization Using Ionic Liquids as Solvent

Paclitaxel (PTX) is a poor water-soluble antineoplastic drug with significant antitumor activity. However, its low bioavailability is a major obstacle for its biomedical applications. Thus, this experiment is designed to prepare PTX crystal powders through an antisolvent precipitation process using...

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Main Authors: Qilei Yang (Author), Chang Zu (Author), Wengang Li (Author), Weiwei Wu (Author), Yunlong Ge (Author), Lingling Wang (Author), Li Wang (Author), Yong Li (Author), Xiuhua Zhao (Author)
Format: Book
Published: MDPI AG, 2020-10-01T00:00:00Z.
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