Studying the association between single nucleotide polymorphisms of metabolizing enzymes and the therapeutic serum levels of calcineurin inhibitors in Egyptian liver transplant patients

Abstract Background Many clinical variables might impact the pharmacokinetics of calcineurin inhibitors (CIs). Different alleles of cytochromes P450 (CYP)3A4/5 and drug transporter P-glycoprotein are the main variables. Other variables include relocated type, treatment duration after transplantation...

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Main Authors: Nermeen N. Abuelsoud (Author), Mohamed Bahaa (Author), Sara A. Osman (Author), Nouran Younis (Author), Mohamed M. Kamal (Author)
Format: Book
Published: SpringerOpen, 2024-11-01T00:00:00Z.
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