Bioprocess optimization of interferon β-1-a in Pichia pastoris and its improved inhibitory effect against hepatocellular carcinoma cells

• Үндсэн зохиолчид: Nasim Moatamedi (Зохиогч), Rahman Emamzadeh (Зохиогч), Hamid Mir Mohammad Sadeghi (Зохиогч), Vajihe Akbari (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Universidade de São Paulo, 2022-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Interferon-β-1a (INF-β-1a) has gained significant attention due to its emerging applications in the treatment of different human diseases. Therefore, many researchers have attempted to produce it in large quantities and also in a biologically active form using different expression systems....