Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma

• Những tác giả chính: Mingchao Wang (Tác giả), Alessio Malfanti (Tác giả), Chiara Bastiancich (Tác giả), Véronique Préat (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2023-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

We hypothesized that tocopherol succinate (TOS) and D-α-tocopherol polyethylene2000 succinate (TPGS2000) micelles could work as a drug delivery system while enhancing the anti-cancer efficacy of doxorubicin lauryl hydrazone derivative (DOXC12) for the treatment of glioblastoma. The DOXC12-TOS-TPGS20...