Changes of Proteases, Antiproteases, and Pathogens in Cystic Fibrosis Patients' Upper and Lower Airways after IV-Antibiotic Therapy

• Main Authors: Ulrike Müller (Author), Julia Hentschel (Author), Wibke K. Janhsen (Author), Kerstin Hünniger (Author), Uta-Christina Hipler (Author), Jürgen Sonnemann (Author), Wolfgang Pfister (Author), Klas Böer (Author), Thomas Lehmann (Author), Jochen G. Mainz (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. In cystic fibrosis (CF) the upper (UAW) and lower airways (LAW) are reservoirs for pathogens like Pseudomonas aeruginosa. The consecutive hosts' release of proteolytic enzymes contributes to inflammation and progressive pulmonary destruction. Objectives were to assess dynamics of pr...