Molecular cloning and characterization of taurocyamine kinase from Clonorchis sinensis: a candidate chemotherapeutic target.

• Main Authors: Jing-Ying Xiao (Author), Ji-Yun Lee (Author), Shinji Tokuhiro (Author), Mitsuru Nagataki (Author), Blanca R Jarilla (Author), Haruka Nomura (Author), Tae Im Kim (Author), Sung-Jong Hong (Author), Takeshi Agatsuma (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Adult Clonorchis sinensis lives in the bile duct and causes endemic clonorchiasis in East Asian countries. Phosphagen kinases (PK) constitute a highly conserved family of enzymes, which play a role in ATP buffering in cells, and are potential targets for chemotherapeutic agents, since va...