Clinical outcomes following identification of an incidental p53 signature in the fallopian tube

• Main Authors: Emily C. MacARTHUR (Author), Mackenzy RADOLEC (Author), T. Rinda SOONG (Author), Esther ELISHAEV (Author), Ronald BUCKANOVICH (Author), Sarah E. TAYLOR (Author), Jamie LESNOCK (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fallopian tube pathology in patients with BRCA1 and BRCA2 mutations suggests a possible pathway to high grade serous ovarian carcinoma originates with a p53 signature, which is thought to represent a potential precursor to serous tubal intraepithelial carcinoma (STIC). The clinical implications of a...