Glucocorticoid induced TNFR-related protein (GITR) as marker of human regulatory T cells: expansion of the GITR+CD25- cell subset in patients with systemic lupus erythematosus

• Main Authors: E. Bartoloni Bocci (Author), R. Bianchini (Author), O. Bistoni (Author), G. Nocentini (Author), A. Alunno (Author), C. Riccardi (Author), R. Gerli (Author)
• Format: Book
• Published: PAGEPress Publications, 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Regulatory T cells (TREG) represent a T cell subset able to modulate immune response by suppressing autoreactive T-lymphocytes. The evidence of a reduced number and an impaired function of this cell population in autoimmune/ inflammatory chronic diseases led to the hypothesis of its invo...