Unscrambling cancer genomes via integrated analysis of structural variation and copy number

Unscrambling cancer genomes via integrated analysis of structural variation and copy number

Summary: Complex somatic genomic rearrangements and copy number alterations are hallmarks of nearly all cancers. We have developed an algorithm, LINX, to aid interpretation of structural variant and copy number data derived from short-read, whole-genome sequencing. LINX classifies raw structural var...

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Main Authors: Charles Shale (Author), Daniel L. Cameron (Author), Jonathan Baber (Author), Marie Wong (Author), Mark J. Cowley (Author), Anthony T. Papenfuss (Author), Edwin Cuppen (Author), Peter Priestley (Author)
Format: Book
Published: Elsevier, 2022-04-01T00:00:00Z.
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