Quantitative Proteomic Analysis Reveals the Sites Related to Acetylation and Mechanism of ACY-1215 in Acute Liver Failure Mice

• Päätekijät: Wen-bin Zhang (Tekijä), Hai-yue Zhang (Tekijä), Yao Wang (Tekijä), Fang-zhou Jiao (Tekijä), Lu-wen Wang (Tekijä), Zuo-jiong Gong (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background: ACY-1215 is a well-known selective histone deacetylase 6 (HDAC6) inhibitor, and it has been considered as a potential therapeutic drug in inflammatory diseases, including acute liver failure (ALF). However, little is known about the impact of ACY-1215 treatment on histone lysine acetylat...