Clonorchis sinensis antigens alter hepatic macrophage polarization in vitro and in vivo.

• Main Authors: Eun-Min Kim (Author), You Shine Kwak (Author), Myung-Hee Yi (Author), Ju Yeong Kim (Author), Woon-Mok Sohn (Author), Tai-Soon Yong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clonorchis sinensis infection elicits hepatic inflammation, which can lead to cholangitis, periductal hepatic fibrosis, liver cirrhosis, and even cholangiocarcinoma. Hepatic macrophages are an intrinsic element of both innate and acquired immunity. This study was conducted to demonstrate the dynamic...