Unraveling the Hippocampal Molecular and Cellular Alterations behind Tramadol and Tapentadol Neurobehavioral Toxicity

• Үндсэн зохиолчид: Cristiana Soares-Cardoso (Зохиогч), Sandra Leal (Зохиогч), Susana I. Sá (Зохиогч), Rita Dantas-Barros (Зохиогч), Ricardo Jorge Dinis-Oliveira (Зохиогч), Juliana Faria (Зохиогч), Joana Barbosa (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2024-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Tramadol and tapentadol are chemically related opioids prescribed for the analgesia of moderate to severe pain. Although safer than classical opioids, they are associated with neurotoxicity and behavioral dysfunction, which arise as a concern, considering their central action and growing misuse and...