Serum Matrix Metalloproteinase-3 as a Noninvasive Biomarker of Histological Synovitis for Diagnosis of Rheumatoid Arthritis

• Main Authors: Jian-Da Ma (Author), Jing-Jing Zhou (Author), Dong-Hui Zheng (Author), Le-Feng Chen (Author), Ying-Qian Mo (Author), Xiu-ning Wei (Author), Li-Juan Yang (Author), Lie Dai (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To explore the correlation between matrix metalloproteinase- (MMP-) 3 and histological synovitis in rheumatoid arthritis (RA). Methods. Serum MMP-3 of 62 patients with active RA was detected by ELISA. Serial synovial tissue sections from all RA patients, 13 osteoarthritis, and 10 orthoped...