SULF 1 gene polymorphism, rs6990375 is in significant association with fetus failure in IVF technique

• Main Authors: Eskandar Taghizadeh (Author), Seyed Mehdi Kalantar (Author), Reza Mahdian (Author), Mohammad Hasan Sheikhha (Author), Ehsan Farashahi-Yazd (Author), Saeed Ghasemi (Author), Zahra Shahbazi (Author)
• Format: Book
• Published: Shahid Sadoughi University of Medical Science, Yazd, Iran, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Sulfatase 1 (SULF1) function is to remove the 6-O-sulphate group from heparan sulfate. This action changes the binding sites of extracellular growth factors. SULF1 expression has been reported to be changed in angiogenesis. We hypothesized that single nucleotide polymorphisms (SNPs) of S...