Multiple-instance-learning-based detection of coeliac disease in histological whole-slide images

• Main Authors: J. Denholm (Author), B.A. Schreiber (Author), S.C. Evans (Author), O.M. Crook (Author), A. Sharma (Author), J.L. Watson (Author), H. Bancroft (Author), G. Langman (Author), J.D. Gilbey (Author), C.-B. Schönlieb (Author), M.J. Arends (Author), E.J. Soilleux (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We present a multiple-instance-learning-based scheme for detecting coeliac disease, an autoimmune disorder affecting the intestine, in histological whole-slide images (WSIs) of duodenal biopsies. We train our model to detect 2 distinct classes, normal tissue and coeliac disease, on the patch-level,...