Transdermal pilocarpine on the skin over salivary glands to increase salivation: an in vivo study

• Main Authors: Natsuko Ishida (Author), Ayano Katsura (Author), Koichi Takagaki (Author), Hiroshi Arakawa (Author), Tsutomu Shimada (Author), Satoshi Mizuno (Author), Yoshimichi Sai (Author), Yukio Kato (Author), Hiroyuki Nakamura (Author), Yukio Suga (Author), Ryo Matsushita (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hyposalivation is treated using oral cholinergic drugs; however, systemic side effects occasionally lead to discontinuation of treatment. We aimed to investigate the effects of transdermal pilocarpine on the salivary gland skin on saliva secretion and safety in rats. Methods Pilo...