Neuroprotective effects of Danshensu on rotenone-induced Parkinson's disease models in vitro and in vivo

• Main Authors: Tian Wang (Author), Cuiting Li (Author), Bing Han (Author), Zhenhua Wang (Author), Xiaoyu Meng (Author), Leiming Zhang (Author), Jie He (Author), Fenghua Fu (Author)
• Format: Book
• Published: BMC, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Danshensu is an active constituent in the extracts of Danshen which is a traditional Chinese medical herb. Rotenone inhibits complex I of the mitochondrial electron transport chain in dopaminergic neurons leading to glutathione (GSH) level reduction and oxidative stress. The aim...