The Intron 4 Polymorphism in the Calcium-Sensing Receptor Gene in Diabetes Mellitus and its Chronic Complications, Diabetic Nephropathy and Non-Diabetic Renal Disease

• Main Authors: Viera Železníková (Author), Marcela Vedralová (Author), Anna Kotrbová-Kozak (Author), Hana Zoubková (Author), Marie Černá (Author), Ivan Rychlík (Author)
• Format: Book
• Published: Karger Publishers, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Calcium-Sensing Receptor (CaSR) significantly affects calcium-phosphate metabolism in kidneys, and it is implicated in the pathogenesis of diabetes mellitus (DM) due to its expression in pancreatic F-cells. The role of CaSR as one of the players in pathogenesis of chronic kidney dis...