Her-2/neu overexpression is associated with thrombospondin-1-related angiogenesis and thrombospondin-1-unrelated lymphangiogenesis in breast cancer

• Asıl Yazarlar: Ming-Chuan Hong (Yazar), Cheng-Yu Long (Yazar), Yu-Feng Tian (Yazar), Ming-Ping Wu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wolters Kluwer Medknow Publications, 2013-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Introduction: Her-2/neu overexpression is linked to poor prognosis and is a significant predictor of the response to trastuzumab (i.e., herceptin) therapy in breast cancer patients. Her-2/neu promotes angiogenesis with thrombospondin-1 (TSP-1) as a mediator in breast cancer development and progressi...