Case Report: EBV Chronic Infection and Lymphoproliferation in Four APDS Patients: The Challenge of Proper Characterization, Therapy, and Follow-Up

Activated PI3K-kinase Delta Syndrome (APDS) is an autosomal-dominant primary immunodeficiency (PID) caused by the constitutive activation of the PI3Kδ kinase. The consequent hyperactivation of the PI3K-Akt-mTOR pathway leads to an impaired T- and B-cells differentiation and function, causing progres...

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主要な著者: Beatrice Rivalta (著者), Donato Amodio (著者), Cinzia Milito (著者), Maria Chiriaco (著者), Silvia Di Cesare (著者), Carmela Giancotta (著者), Francesca Conti (著者), Veronica Santilli (著者), Lucia Pacillo (著者), Cristina Cifaldi (著者), Maria Giovanna Desimio (著者), Margherita Doria (著者), Isabella Quinti (著者), Rita De Vito (著者), Gigliola Di Matteo (著者), Andrea Finocchi (著者), Paolo Palma (著者), Antonino Trizzino (著者), Alberto Tommasini (著者), Caterina Cancrini (著者)
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出版事項: Frontiers Media S.A., 2021-08-01T00:00:00Z.
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