Emodin Rescues Intrahepatic Cholestasis via Stimulating FXR/BSEP Pathway in Promoting the Canalicular Export of Accumulated Bile

• Автори: Xiao-Li Xiong (Автор), Yan Ding (Автор), Zhi-Lin Chen (Автор), Yao Wang (Автор), Pan Liu (Автор), Huan Qin (Автор), Li-Shan Zhou (Автор), Ling-Ling Zhang (Автор), Juan Huang (Автор), Lei Zhao (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

AimBile salt export pump (BSEP) have been confirmed to play an important role for bile acid canalicular export in the treatment of cholestasis. In this study, we investigated the stimulatory effect of emodin on BSEP signaling pathway in cholestasis.MethodsCell and animal experiments were given diffe...