SEL1L plays a major role in human malignant gliomas

• Main Authors: Marta Mellai (Author), Laura Annovazzi (Author), Renzo Boldorini (Author), Luca Bertero (Author), Paola Cassoni (Author), Pasquale De Blasio (Author), Ida Biunno (Author), Davide Schiffer (Author)
• Format: Book
• Published: Wiley, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Suppressor of Lin‐12‐like (C. elegans) (SEL1L) participates in the endoplasmic reticulum‐associated protein degradation pathway, malignant transformation and stem cell biology. We explored the role of SEL1L in 110 adult gliomas, of different molecular subtype and grade, in relation to cell...