Phage therapy is effective against infection by Mycobacterium ulcerans in a murine footpad model.

• Main Authors: Gabriela Trigo (Author), Teresa G Martins (Author), Alexandra G Fraga (Author), Adhemar Longatto-Filho (Author), António G Castro (Author), Joana Azeredo (Author), Jorge Pedrosa (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Buruli Ulcer (BU) is a neglected, necrotizing skin disease caused by Mycobacterium ulcerans. Currently, there is no vaccine against M. ulcerans infection. Although the World Health Organization recommends a combination of rifampicin and streptomycin for the treatment of BU, clinical mana...