Response to Infliximab in Crohn's Disease: Genetic Analysis Supporting Expression Profile

• Main Authors: Luz María Medrano (Author), Carlos Taxonera (Author), Cristina González-Artacho (Author), Virginia Pascual (Author), María Gómez-García (Author), Manuel Barreiro-de Acosta (Author), José L. Pérez-Calle (Author), Fernando Bermejo (Author), Antonio López-Sanromán (Author), Dolores Martín Arranz (Author), Javier P. Gisbert (Author), Juan Luis Mendoza (Author), Javier Martín (Author), Concepción Núñez (Author), Elena Urcelay (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Substantial proportion of Crohn's disease (CD) patients shows no response or a limited response to treatment with infliximab (IFX) and to identify biomarkers of response would be of great clinical and economic benefit. The expression profile of five genes (S100A8-S100A9, G0S2, TNFAIP6, and IL11...