Regulation of P450 oxidoreductase by gonadotropins in rat ovary and its effect on estrogen production

• Main Authors: Uesaka Miki (Author), Kangawa Kenji (Author), Kokame Koichi (Author), Mizutani Tetsuya (Author), Yazawa Takashi (Author), Inaoka Yoshihiko (Author), Umezawa Akihiro (Author), Miyamoto Kaoru (Author)
• Format: Book
• Published: BMC, 2008-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>P450 oxidoreductase (POR) catalyzes electron transfer to microsomal P450 enzymes. Its deficiency causes Antley-Bixler syndrome (ABS), and about half the patients with ABS have ambiguous genitalia and/or impaired steroidogenesis. POR...