Case Report: Intestinal Nodular Lymphoid Hyperplasia as First Manifestation of Activated PI3Kδ Syndrome Due to a Novel PIK3CD Variant

• Main Authors: Antonio Marzollo (Author), Silvia Bresolin (Author), Davide Colavito (Author), Alice Cani (Author), Paola Gaio (Author), Luca Bosa (Author), Claudia Mescoli (Author), Linda Rossini (Author), Federica Barzaghi (Author), Giorgio Perilongo (Author), Alberta Leon (Author), Alessandra Biffi (Author), Mara Cananzi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nodular lymphoid hyperplasia (NLH) is a lymphoproliferative disease caused by non-clonal expansion of lymphoid cells in the gut mucosa. Little is known about the pathogenesis of NLH, which is often disregarded as an insignificant or para-physiologic phenomenon. We present the case of a girl with iso...