Heat Shock Protein Inhibitor 17-Allyamino-17-Demethoxygeldanamycin, a Potent Inductor of Apoptosis in Human Glioma Tumor Cell Lines, Is a Weak Substrate for ABCB1 and ABCG2 Transporters

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and has a poor prognosis. Complex genetic alterations and the protective effect of the blood-brain barrier (BBB) have so far hampered effective treatment. Here, we investigated the cytotoxic effects of heat shock protein...

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Main Authors: Nikola Pastvova (Author), Petr Dolezel (Author), Petr Mlejnek (Author)
Format: Book
Published: MDPI AG, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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