Two in One: Use of Divalent Manganese Ions as Both Cross-Linking and MRI Contrast Agent for Intrathecal Injection of Hydrogel-Embedded Stem Cells

• Main Authors: Lukasz Kalkowski (Author), Dominika Golubczyk (Author), Joanna Kwiatkowska (Author), Piotr Holak (Author), Kamila Milewska (Author), Miroslaw Janowski (Author), Joaquim Miguel Oliveira (Author), Piotr Walczak (Author), Izabela Malysz-Cymborska (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cell therapy is a promising tool for treating central nervous system (CNS) disorders; though, the translational efforts are plagued by ineffective delivery methods. Due to the large contact surface with CNS and relatively easy access, the intrathecal route of administration is attractive in extensiv...