On the Mechanism of Levosimendan-Induced Dopamine Release in the Striatum of Freely Moving Rats

• Main Authors: Gaia Rocchitta (Author), M. Rosaria Delogu (Author), Rossana Migheli (Author), Luigi Solinas (Author), Giuseppe Susini (Author), Maria S. Desole (Author), Egidio Miele (Author), Maddalena Miele (Author), Pier Andrea Serra (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Ca2+ sensitizer levosimendan (LEV) improves myocardial contractility by enhancing the sensitivity of the contractile apparatus to Ca2+. In addition, LEV promotes Ca2+ entry through L-type channels in human cardiac myocytes. In this study, which was performed using microdialysis, infusion of LEV...