siRNA-Mediated Silencing of doublesex during Female Development of the Dengue Vector Mosquito Aedes aegypti.

• Main Authors: Keshava Mysore (Author), Longhua Sun (Author), Michael Tomchaney (Author), Gwyneth Sullivan (Author), Haley Adams (Author), Andres S Piscoya (Author), David W Severson (Author), Zainulabeuddin Syed (Author), Molly Duman-Scheel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of sex-specific traits, including the female-specific ability to bite humans and vector disease, is critical for vector mosquito reproduction and pathogen transmission. Doublesex (Dsx), a terminal transcription factor in the sex determination pathway, is known to regulate sex-specifi...